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Zopiclone (brand names Zimovane and Imovane) is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid in the central nervous system, via modulating benzodiazepine receptors in the same way that benzodiazepine drugs do.

As zopiclone is sedating, it is marketed as a sleeping pill. It works by causing a depression or tranquilization of the central nervous system. After prolonged use, the body can become accustomed to the effects of zopiclone. When the dose is then reduced or the drug is abruptly stopped, withdrawal symptoms may result. These can include a range of symptoms similar to those of benzodiazepine withdrawal. Although withdrawal from therapeutic doses of zopiclone and its isomers (i.e. eszopiclone) do not typically present with convulsions and are therefore not considered life-threatening

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Buy Zopiclone is a tranquilizer with sedative and hypnotic effects of the action. It Activates GABA-ergic mechanisms of synaptic transmission in the brain. Zopiclone is also indicated for use in the treatment of deficiency syndrome of sleep different Genesis, including those associated with depression, and in combination with theophylline – attacks of nocturnal asthma.

Zopiclone therefore reduces trimipramine concentration in the blood (with the joint use of these drugs weakens its analeptic effect), but is able to increase the effects of sedation and alcohol. The drug is not indicated for hypersensitivity, severe respiratory failure, pregnancy, breast-feeding. Buy Zopiclone

Indications for use

More to that its used for the Treatment of primary sleep disorders: sleep difficult, night and early awakenings, transient situational or chronic insomnia; secondary sleep disorders and mental disorders in situations that significantly worsen the patient’s condition. Testimony is limited to serious sleep disorders in the following cases: Buy Zopiclone

  • temporary insomnia;
  • short – term insomnia.

Contraindications

Carefully read the contraindications before you buy zopiclone online. The drug is contraindicated in hypersensitivity to Zopiclone or other components of the drug, night apnea syndrome, decompensated respiratory failure, severe acute or chronic liver failure (due to risk of encephalopathy), myasthenia gravis, pregnancy, lactation, children up to the ages 18 years. Buy Zopiclone

Method of application and doses

Treatment with zopiclone without prescription should always start with the lowest effective dose and should never exceed the maximum dose. Therefore you should only take these sleeping pills when you are able to get a full night of sleep.

The usual does the following:

  • for adults under 65 years of age: 7.5 mg per day;
  • for elderly patients over 65 years of age the recommended dose of 3.75 mg per day; only in exceptional cases, use of 7.5 mg per day;
  • for patients with severe hepatic insufficiency the recommended dose of Zopiclone is 3.75 mg;
  • for patients with failure of respiratory function moderate recommended dose of 3.75 mg per day;

So therefore, In all cases, the daily dose of Zopiclone should not exceed 7.5 mg

Duration of treatment with zopiclone online

Treatment should be as short as possible, lasting from several days to 4 weeks including the period of dose reduction. You must specify to the patient, what is the exact duration of the treatment

  • from 2 to 5 days in case of temporary insomnia (for example, due to the change of places);
  • 2 to 3 weeks for short term insomnia (e.g., caused by a serious event in my life).

Though some cases may require longer treatment beyond the recommended period. In such cases, mandatory repeated and thorough assessment of the patient before using zopiclone over the counter.

Side effects

To doses which are recommended, the drug is well tolerated and has a low frequency postranecky violations. The most frequent side effect during treatment with Zopiclone is a moderate sensation of bitter or metallic taste in the mouth. More to that, you may experience the following side effects below: Buy Zopiclone

  • anterograde amnesia, which can occur at therapeutic doses and the risk increases with the dose;
  • breach of conduct, a change of consciousness, irritability, depressed mood, aggressiveness, restlessness and also sleepwalking;
  • physical and psychological dependence, even at therapeutic doses, withdrawal symptoms or rebound insomnia upon discontinuation of treatment with zopiclone online;
  • dizziness, headache, in exceptional cases and ataxia;
  • confusion, hallucinations, impaired alertness or even drowsiness (especially in elderly), insomnia, nightmares and tension;
  • change in libido;
  • rash and itching;
  • diplopia;
  • muscular hypotonia, asthenia, anaphylactic reaction, urticaria and angiodema;
  • gastrointestinal disorders: nausea, vomiting, dyspepsia, dryness and metallic taste in the mouth;
  • increase in liver enzymes;
  • very rarely increased the levels of transaminase or alkaline phosphatase, which in some cases may result in a clinical picture of liver damage.
  • Upon awakening there may be drowsiness, sometimes dizziness and loss of coordination.

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